Enzymes Dr Mercola

Enzymes ................. Dr. Mercola

You've probably heard of enzymes, and you probably already know they are important for your digestion. But you may not be aware of just how necessary enzymes are to every cell in your body—not just for digestion but for ALL your physiological processes.

Enzymes are composed of amino acids and are secreted by your body to help catalyze functions that would normally not occur at physiological temperatures. They literally make magic happen and are absolutely vital to your life.

More than 3,000 different enzymes have been identified, and some experts believe there may be another 50,000 we have yet to discover. Each enzyme has a different function—like 3,000 specialized keys cut to fit 3,000 different locks. In this analogy, the locks are biochemical reactions.

Enzymes drive biological processes necessary for your body to build raw materials, circulate nutrients, eliminate unwanted chemicals, and the myriad of other biochemical processes that go on without your even thinking about it.

For starters, here are just some of the activities in your body requiring enzymes:

  • Energy production
  • Absorption of oxygen
  • Fighting infections and healing wounds
  • Reducing inflammation
  • Getting nutrients into your cells
  • Carrying away toxic wastes
  • Breaking down fats in your blood, regulating cholesterol and triglyceride levels
  • Dissolving blood clots
  • Proper hormone regulation
  • Slowing the aging process

And small amounts of enzymes can affect profound changes! Enzymes are the catalysts that cause many essential biochemical reactions to happen—but they are not "used up" IN the reaction. They merely assist—meaning, they accelerate reactions—sometimes to a mind-boggling several million reactions per second!

Enzymes lower the amount of energy needed for a reaction to occur. Without them, some reactions simply would not function in your body.

But enzymes don't work alone.

Enzymes rely on other elements to accomplish their tasks, such as certain vitamins and minerals. These elements are called "coenzymes."

You are probably already familiar with one of these—coenzyme Q10. CoQ10 is found in the mitochondria (power centers) of your cells where it is involved in making ATP, every cell's principal energy source. Another example is magnesium, which participates in over 300 enzyme reactions.

The Concept of "Enzyme Potential"

Dr. Edward Howell spent his entire professional life studying enzymes and can be credited with catalyzing enzyme research.

Whether or not this is true, Howell believed you were born with a limited enzyme-producing capacity, and that your life expectancy depends on how well you preserve your "enzyme potential." His theory was that if you don't get enough enzymes from the food you eat, great strain is placed on your digestive system to "pick up the slack," i.e., produce enough enzymes to accomplish the task.

A deficiency in digestive enzymes then reduces availability of your metabolic enzymes. Howell believed this metabolic enzyme deficit was at the root of most chronic health problems.

Enzyme Basics

There are three basic categories of enzymes:

  1. 1.Digestive
  2. 2.Metabolic
  3. 3.Food based

Digestive enzymes, as their name implies, help you break down food into smaller parts that can be absorbed, transported and utilized by every cell in your body. Digestive enzymes are extra-cellular—meaning, they are found outside your cells.

Metabolic enzymes are intra-cellular—meaning, inside your cells, where they help the cell carry out a variety of functions related to its reproduction and replenishment.

Your pancreas produces most of these digestive and metabolic enzymes.

Fortunately, you get (or should be getting) many enzymes from the foods you consume—particularly, raw foods. These directly help with your digestive process.

The more raw foods you eat, the lower the burden on your body to produce the enzymes it needs, not only for digestion, but for practically everything. Whatever enzymes are not used up in digestion are then available to help with other important physiological processes.

Your Meal's Journey through Your Digestive System

Once consumed, your meal begins a complicated, multi-phased journey of breakdown and conversion into nutrients your body can use. This process is, of course, called digestion, and enzymes play a key role.

There are eight primary digestive enzymes, each designed to help break down different types of food:

  1. 1.Protease: Digesting protein
  2. 2.Amylase: Digesting carbohydrates
  3. 3.Lipase: Digesting fats
  4. 4.Cellulase: Breaking down fiber
  5. 5.Maltase: Converting complex sugars from grains into glucose
  6. 6.Lactase: Digesting milk sugar (lactose) in dairy products
  7. 7.Phytase: Helps with overall digestion, especially in producing the B vitamins
  8. 8.Sucrase: Digesting most sugars

Digestion begins in your mouth, starting with saliva. Did you know that you produce about 1.7 liters of saliva each day? Your mouth is where enzymes (primarily amylase) begin to exert their action. Amylase in your saliva begins to break down carbohydrates.

As food passes into your stomach, proteins are worked on by protease. From there, the bolus of food passes into your small intestine, where lipase begins to break down fats, and amylase finishes off the carbohydrates.

Did you know that 90 percent of your digestion and absorption takes place in your small intestine?

From here, the micronutrients are absorbed into your bloodstream through millions of tiny villi in the wall of your gut. But what happens when this process goes awry?

Disease—or "dis-ease."

Aftermath of the Western Diet: Enzyme Deficiency

Insufficient enzyme production is at the root of much "tummy trouble" in our country. Digestive problems cost Americans $50 billion each year in both direct costs and absence from work.

It is a sad fact that 90 percent of the food Americans buy is processed food. Diets heavy in cooked, processed, and sugary foods, combined with overuse of pharmaceutical drugs such as antibiotics, deplete your body's ability to make enzymes.

Enzymes may be relatively large, but their protein structures are fragile. The amino acids in the molecular chain link together to form certain patterns and shapes, which give enzymes their unique characteristics and functions. When something disrupts the chain's structure, the enzyme becomes "denatured"—it changes shape and loses its ability to perform.

Heating your food above 116 degrees F renders most enzymes inactive.

This is one of the reasons it's so important to eat your foods raw. Raw foods are enzyme-rich, and consuming them decreases your body's burden to produce its own enzymes. The more food that you can eat raw, the better. Ideally, you should get 75 percent of your digestive enzymes from your food.

In addition to heat, enzymes are also very sensitive to shifts in pH, which is why different enzymes work in different parts of your digestive tract, based on the pH each enzyme needs in order to function.

Enzyme deficiency results in poor digestion and poor nutrient absorption. This creates a variety of gastrointestinal symptoms, including:

Chronic malabsorption can lead to a variety of illnesses. Think about it—if your body doesn't have the basic nutritional building blocks it needs, your health and ability to recover from illness will be compromised.

Besides breaking down food, enzymes (particularly the proteases) can help with gut healing, controlling pathogens, and immune support. Your immune system begins in your gut—and if you have enzyme and digestive issues, chances are your immune system isn't functioning as well as it should be.

Complicating matters, your capacity for enzyme production also declines with age.

How Aging Affects Your Enzyme Production

Research has shown that your natural enzyme production starts to decline by the time you're about 20.

Studies show that, every ten years, your body's production of enzymes decreases by 13 percent. So by age 40, your enzyme production could be 25 percent lower than it was when you were a child. And by the time you're 70, you could be producing only ONE-THIRD of the enzymes you need.

Making matters worse, your stomach produces less hydrochloric acid as you age, and hydrochloric acid is crucial in activating your stomach's digestive enzymes.

When digestion of foods requires such a heavy demand, enzyme supplies run short and your enzyme-producing capacity can become exhausted. Why does this matter? The high demand for digestive enzymes depletes your body's production of metabolic enzymes, which every cell in your body needs in order to function.

The Many Roles of Metabolic Enzymes

Now that you know how important digestive enzymes are for getting nourishment, let's take a look at another type of enzymatic activity—your metabolic enzymes. Metabolic enzymes are intimately involved with running your circulatory, lymphatic, cardiac, neurologic, endocrine, renal, hepatic, and reproductive systems, and maintaining your skin, bones, joints, muscles and other tissues.

Every one of your 10 trillion cells depends on these enzymes and their ability to catalyze energy production. As I said before, each of these enzymes is highly specialized as a function of its particular molecular structure.

Consider these two examples:

  • RNA polymerase is an enzyme your body uses to transcribe DNA into RNA, which is used to make proteins.
  • Lysosomal enzyme, produced in the lysosome of each cell (also called the “suicide bag”), breaks down macromolecules and other foreign particles the cell has ingested (such as bacteria) so they can be disposed of. The lysosome is a microscopic garbage disposal!

One of the most important functions of metabolic enzymes happens in your blood. If you think about it, it makes sense. We know that bacteria, fungi, and parasites are comprised of protein, as is the shell encompassing viruses. Enzymes in your blood—primarily proteases (proteolytic enzymes)—serve to break down protein-based foreign bodies, effectively cleansing your blood.

As blood cleansers, these enzymes combat chronic inflammation, which left unchecked can lead to everything from autoimmune diseases, to cardiovascular disease and even cancer. Enzymes reduce inflammation in your body by:

  1. 1.Breaking down foreign proteins in the blood that cause inflammation and facilitating their removal via your blood stream and lymphatic system
  2. 2.Removing “fibrin,” a clotting material that can prolong inflammation
  3. 3.Reducing edema in the inflamed regions

It follows, then, that any disease caused by inflammation—which is practically every chronic disease we face today—can be benefited by increased levels of functional enzymes in your blood.

I will discuss oral enzyme supplementation shortly. Although taking an enzyme supplement may be helpful, NO manufactured product can duplicate the positive effects of a nutrient-rich diet.

Boosting Your Enzyme Levels Naturally

There are four ways to naturally increase your enzyme levels:

  1. 1.Increase your intake of raw, living foods
  2. 2.Eat fewer calories
  3. 3.Chew your food thoroughly
  4. 4.Avoid chewing gum

The very best way to get enzymes into your body is by consuming at least 75 percent of your foods raw. For many of you, you'll have to work toward this goal gradually.

While all raw foods contain enzymes, the most powerful enzyme-rich foods are those that are sprouted (seeds and legumes). Sprouting increases the enzyme content in these foods tremendously. Besides sprouts, other enzyme-rich foods include:

The best way to bump up your metabolic enzymes is to provide your body with the raw materials and energy it needs to make them. By eating these types of foods, you supply your body with the amino acids and the enzyme co-factors needed to boost your own natural enzyme production.

Another way to lower your body's demand for enzymes is to reduce your caloric intake. Did you know the average person spends 80 percent of his available energy simply digesting food?

By reducing overall consumption, as well as introducing more living foods, you reduce your need for digestive enzymes, which allows your body to put more of its energy into producing metabolic enzymes.

Which brings us to chewing. Quite apart from the esthetic pleasure of an unhurried meal, there are important physiological reasons to chew your food well.

Chewing stimulates saliva production, and the more time you spend chewing, the longer your saliva enzymes have to work in your mouth, lessening the workload of your stomach and small intestine. Chewing also stimulates a reflex that sends a message to your pancreas and other digestive organs, "Gear up—we've got incoming!"

And don't chew gum.

Chewing gum fools your body into believing it is digesting something, so it pumps out digestive enzymes unnecessarily. Why waste those precious resources?

Digestive Enzyme Supplementation

If you suffer from occasional bloating, minor abdominal discomfort, and occasional constipation and suspect your enzyme production is low, you might want to consider a digestive enzyme supplement in addition to eating more of your foods raw.

Digestive enzymes should be taken WITH a meal. There are hundreds on the market, so how do you choose a good one? You should look for an enzyme formula with the following characteristics:

  • It should contain a mixture of different types of enzymes, to help digest all of the different components of your diet (including lipase, protease, and amylase)
  • The ingredients should be high quality, all-natural, and free of allergens and additives
  • The supplement should be labeled as to the enzymatic strength of each ingredient, not just its weight
  • It should be made by a reputable company with rigorous quality control and testing for potency

Besides digestive enzyme supplementation, there is another way to use oral enzymes—for systemic use. This requires taking enzymes between meals so they can be absorbed through your gut and into your bloodstream, where your cells can use them metabolically.

Systemic Enzymes—Playing Catch-Up with European Medicine

Getting enzymes from your digestive tract into your bloodstream isn't as easy as it would seem. As I've already discussed, enzymes are very susceptible to denaturing and must be helped to survive the highly acidic environment in your stomach. They are often given an "enteric coating" to help them survive the journey through your digestive tract.

And then, there is the matter of absorption.

For nearly 100 years, medical dogma insisted that enzymes taken orally were too large to pass through the digestive tract wall.

However, there is now a good deal of research that they can indeed pass through your intestine intact and into your bloodstream and lymphatic system, where they can deliver their services to the rest of your body... one of the mysteries of medical science.

Now that we know this is possible, systemic oral enzymes have been used to treat problems ranging from sports injuries to arthritis to heart disease and cancer, particularly in European countries. But most of the research has been published in non-English language journals.

This systemic use of enzymes is just now taking off in the United States.

It is crucial that, in order for enzymes to be used systemically, they must be ingested on an empty stomach. Otherwise, your body will use them for digesting your food, instead of being absorbed into the blood and doing their work there.

Let's take a look at how systemic enzymes can benefit your health by examining their applications for two major health problems we face today: heart disease and cancer.

How Systemic Enzymes Battle Heart Disease

It is now fairly well recognized that heart attacks and strokes are related to inflammation, which is why C-reactive protein (an inflammatory marker) can be predictive of cardiac events.

However, according to an excellent article about systemic enzymes by Michael Sellar, French researchers have proposed that bacteria might be a causative factor in coronary artery disease. Very high levels of bacteria were found in their patients' arterial plaques, possibly explaining elevations in C-reactive protein.

C-reactive protein functions to stop the spread of bacteria in your body.

Since enzymes inhibit platelet aggregation, help your immune system combat pathogens, and break down fibrin (which makes up clots), they may offer significant benefits for vascular diseases like thrombosis, phlebitis, and varicose veins.

Sellar quotes enzyme researcher Rudolph Kunze:

"Although enzymes reduce inflammation and we used to think that was all they did, we now believe that the central target of systemic enzymes is the immune system. It is my belief that heart disease is an immune disease very much, although obviously not totally, related to bacterial pathogens and other invaders."

Systemic Enzymes in the Treatment of Cancer

The use of enzymes to treat cancer has its roots all the way back to 1911 with John Beard's The Enzyme Treatment of Cancer and Its Scientific Basis. Beard believed cancer was a result of diminished pancreatic enzymes, impairing your immune response.

A study in 1999 suggests he may have been right on target.

Ten patients with inoperable pancreatic cancer were treated with large doses of oral pancreatic enzymes (along with detoxification and an organic diet), and their survival rates were 3 to 4 times higher than patients receiving conventional treatment. Proteolytic enzymes can be helpful in treating cancer because they help restore balance to your immune system.

Dr. Nick Gonzalez in New York City, NY has also done a lot of work on enzymes in cancer treatment and has written a book on the subject.

Some of the ways proteolytic enzymes can be helpful in the fight against cancer are:

  • Boosting cytokines, particularly interferon and tumor necrosis factor, which are very important warriors in destroying cancer cells.
  • Decreasing inflammation.
  • Dissolving fibrin: Cancer cells hide under a cloak of fibrin to escape detection. Once the cancer cells are “uncloaked,” they can be spotted and attacked by your immune system. It is also thought that fibrin makes cancer cells “stick together,” which increases the chance for metastases.
  • German studies have shown that systemic enzymes increase the potency of macrophages and killer cells 12-fold.

For more about the difference between digestive enzymes and systemic enzymes, click here for a video interview with enzyme expert Nena Dockery.

Hopefully you can now appreciate just how important enzymes are to your overall health, right down to the cellular level. Once you understand this, you may begin to see just how important it is to eat a diet rich in fresh, organic, raw foods. You may even want to try juicing some of your vegetables as a way of getting more nutrients—and enzymes—into your body.

It has been said, "You are what you eat." But really, "You are what you digest" is closer to the truth.

Magnesium Dr Mercola

Dr Mercola ................Magnesium

Every cell in your body depends on magnesium to function. This includes your teeth, bones, hormones, nervous system and your heart. The highest concentrations of magnesium in your body are actually in your heart and your brain, which is why a deficiency can actually be deadly.

Magnesium Deficiency Increases Your Risk of Death

We are all going to die at some point, but if you're deficient in magnesium you may wind up dying sooner rather than later. As new research in Atherosclerosis found, low serum magnesium levels are associated with higher all-cause mortality and cardiovascular mortality, adding to growing research supporting the importance of adequate magnesium.

In one long-term study, published in the American Journal of Clinical Nutrition, researchers found that the relative risk of sudden cardiac death (SCD) was significantly lower in women with the highest amounts of magnesium. Each 0.25-mg/dL increment in plasma magnesium was associated with a 41 percent lower risk of SCD.

A similar 15-year long study found that people with the highest blood levels of magnesium had a 40 percent reduction in the risk of SCD, compared to those with the lowest magnesium levels.

There is in fact quite a bit of evidence supporting the link between magnesium and heart health, and back in the 1930s doctors used to prescribe magnesium for heart disease. Part of the benefit appears related to its synergistic effect on calcium to help regulate electrical impulses and prevent calcium from depositing in soft tissues.

The Magnesium-Calcium Connection

As written in Magnificent Magnesium, first published in the quarterly magazine of the Weston A. Price Foundation:

"Magnesium works in concert with calcium to regulate electrical impulses in the cell—magnesium concentration inside healthy cells is ten thousand times greater than calcium, and there are crucial reasons for this safeguard.

Cellular calcium channels allow that mineral to enter the cell only as long as needed to conduct an impulse; it is ushered out immediately by magnesium once its task is fulfilled. This vigilance is necessary to prevent calcium accumulation in the cell, which could cause dangerous hyper-excitability, calcification, cell dysfunction and even cell death.

When excess calcium enters the cells because of insufficient magnesium, muscle contraction is sustained for too long, and we suffer, for example, twitches and tics in mild cases. When magnesium deficiency becomes chronic, we suffer the symptoms of heart disease such as angina pectoris, hypertension and arrhythmia, or the spasms and contractions characteristic of asthma, migraine headache or painful menstrual cramping."

In fact, while calcium is typically the mineral associated with strong bones and healthy teeth, calcium depends on magnesium to function properly. In this way it is actually magnesium that is largely responsible for your bone health and strong teeth. The Weston Price Foundation states:

"Bones and teeth certainly do require calcium—as well as phosphorus and magnesium, but without adequate amounts of the latter, calcium will not be deposited in these hard tissues, and the structures will not be sound.

"When you load up your system with excess calcium," writes William Quesnell, in Minerals: the Essential Link to Health, "you shut down magnesium's ability to activate thyrocalcitonin, a hormone that under normal circumstances would send calcium to your bones." Instead of providing benefits to the body, the displaced calcium actually becomes toxic …

Numerous studies, in fact, have established the fact that it is dietary magnesium, not calcium, (and certainly not fluoride) that creates glassy hard tooth enamel that resists decay, and strong and resilient bones."

So if you decide to supplement with magnesium it is important to understand that its complementary partner is calcium. Ideally you should have a source of both, but if you are eating raw dairy there is typically no reason for oral calcium supplementation.  Typically you would use twice as much elemental magnesium relative to the elemental calcium. That ratio seems to work quite well for most people.

The Widespread Benefits of Magnesium

The benefits of magnesium span far beyond your heart health. This mineral is actually responsible for more than 300 biochemical reactions in your body, including the action of your heart muscle, the regulation of blood sugar levels and the promotion of proper bowel function. As the Weston Price Foundation states:

"Magnesium is so important to so many vital body functions, and its deficiency is integrally involved in so many diseases, that more than one researcher has dubbed magnesium a miracle in its ability to resolve or improve numerous disorders. The current list of disorders with direct and confirmed relationships to chronic and acute magnesium deficiency is long, and includes many diseases whose conventional medical treatment does not commonly address magnesium insufficiency."

They note that magnesium deficiency has in fact been implicated in the following conditions:

ADD/ADHD

Alzheimer's disease

Angina pectoris

Anxiety disorders

Arrhythmia

Arthritis (rheumatoid and osteoarthritis)

Asthma

Autism

Autoimmune disorders

Cerebral palsy (in children of magnesium-deficient mothers)

Chronic fatigue syndrome

Congestive heart failure

Constipation

Crooked teeth/narrow jaw (in children of magnesium-deficient mothers)

Dental caries

Depression

Diabetes (type 1 and type 2)

Eating disorders (bulimia and anorexia)

Fibromyalgia

Gut disorders such as peptic ulcer, Crohn's disease, colitis

Heart disease

Hypertension

Hypoglycemia

Insomnia

Kidney stones

Lou Gehrig's disease

Migraines

Mitral valve prolapse

Multiple sclerosis

Muscle cramping, weakness, fatigue

Myopia (in children of magnesium-deficient diet)

Obesity

Osteoporosis

Parkinson's disease

PMS, menstrual pain and irregularities

Primary pulmonary hypertension (PPH)

Reynaud's syndrome

SIDS (sudden infant death syndrome)

Stroke

Thyroid disorders

 

Magnesium also plays a role in your body's detoxification processes and therefore is important for helping to prevent damage from environmental chemicals, heavy metals and other toxins. Even glutathione, your body's most powerful antioxidant that has even been called "the master antioxidant," requires magnesium for its synthesis.

Magnesium Deficiency is a Serious, Endemic Problem

Green leafy vegetables like spinach and Swiss chard are excellent sources of magnesium, as are some beans, nuts and seeds, like almonds, pumpkin seeds, sunflower seeds and sesame seeds. Avocadoes are also a good source. However, surveys suggest that many Americans are not getting enough magnesium in their diets. As the National Institutes of Health Office of Dietary Supplements states:

" … dietary surveys suggest that many Americans do not get recommended amounts of magnesium … there is concern that many people may not have enough body stores of magnesium because dietary intake may not be high enough. Having enough body stores of magnesium may be protective against disorders such as cardiovascular disease and immune dysfunction."

It's been estimated that up to 80 percent of the U.S. population is deficient in this important mineral, according to Carolyn Dean, MD, ND, author of The Miracle of Magnesium. This is true even if you eat foods rich in magnesium, as:

  • Many foods are grown in magnesium-depleted soil
  • Handling, refrigeration, transport and storage of fresh produce can lead to loss in nutrients like magnesium
  • Food processing, such as roasting nuts, milling whole grains for white flour, and cooking greens, can lead to loss of magnesium
  • Magnesium that exists in drinking water binds with fluoride to create, according to the Weston Price Foundation, "a nearly insoluble mineral compound that ends up deposited in the bones, where its brittleness increases the risk of fractures"

What Could be Making You Magnesium Deficient?

See Dr. Natasha Campbell-
McBride and Me Speak
in November


We are both scheduled to speak at the Weston Price Foundation Conference Nov 11-13th.

Please click here for more details.

There are other factors, too, that make it difficult for your body to maintain adequate magnesium levels, particularly if you eat poorly and are under a lot of stress.

As the Weston Price Foundation states:

"A diet of processed, synthetic foods, high sugar content, alcohol and soda drinks all "waste" magnesium, as a lot of it is required for the metabolism and detoxification of these largely fake foods. According to Dr. Natasha Campbell-McBride, the body requires at least twenty-eight molecules of magnesium to metabolize a single molecule of glucose. Phosphates in carbonated drinks and processed meats (so-called "luncheon meats" and hot dogs) bind with magnesium to create the insoluble magnesium phosphate, which is unusable by the body.

Mental and physical stress, with its related continuous flow of adrenaline, uses up magnesium rapidly, as adrenaline affects heart rate, blood pressure, vascular constriction and muscle contraction— actions that all demand steady supplies of magnesium for smooth function."

Many pharmaceutical drugs, including birth control pills, insulin, diuretics, certain antibiotics, and corticosteroids, also contribute to magnesium deficiency. And, of course, you also need a healthy gut environment to absorb minerals in your diet. So if you suffer from irritable bowel syndrome, leaky gut or are using antacids to treat heartburn or acid reflux (this impairs the production of hydrochloric acid in your stomach, which is needed for mineral absorption), there's a good chance you're not absorbing enough magnesium.

With that in mind, some early signs of magnesium deficiency to keep an eye out for include:

  • Loss of appetite
  • Nausea and vomiting
  • Fatigue and weakness

An ongoing magnesium deficiency can lead to:

  • Numbness and tingling
  • Muscle contractions and cramps
  • Seizures
  • Personality changes
  • Abnormal heart rhythms and coronary spasms

What to do if You're Magnesium Deficient

Unfortunately, there's no lab test that will give an accurate reading of the magnesium status in your tissues. Only 1 percent of magnesium in your body is distributed in your blood, which makes a simple blood sample highly inaccurate.

That's why most doctors who rely on blood tests for magnesium, as opposed to looking for signs and symptoms of magnesium deficiency, will frequently miss an important diagnosis.

If you suspect you are low in magnesium, the best way to consume this mineral is through organically bound magnesium, which is found in organic green, leafy vegetables.

Other foods high in magnesium are:

  • Rice, wheat or oat bran
  • Spinach
  • Artichokes
  • Dried herbs
  • Squash pumpkin and watermelon seeds
  • Dark chocolate cocoa powder
  • Flax and sesame seeds
  • Brazil nuts
  • Sunflower seeds
  • Almonds, mixed nuts, pine nuts

Organic foods may contain more magnesium, particularly if the farmer replenishes his soil with magnesium-rich fertilizers. (Factory farms tend to use fertilizers rich in nitrogen, phosphorous, and potassium to make plants grow and appear healthy.)

However, if magnesium and other minerals and micronutrients are not introduced through the soil, the plants may look healthy but will not be packed with the nutrition you need.

As a general rule, to get as much magnesium as possible in your diet, eat plenty of organic leafy green vegetables, nuts and seeds every day. Juicing your vegetables is an excellent option to ensure you're getting enough of them in your diet.

You can also try a high-quality magnesium supplement, such as magnesium citrate or magnesium malate. If you experience loose stools when taking it, it's an indication that it's not being absorbed. If this occurs, try varying your dosage or try a magnesium supplement that is chelated to an amino acid, such as magnesium taurate or magnesium glycinate. Alternatively, you can actually absorb magnesium via your skin by soaking in a bath with Epsom salts, which contain magnesium sulfate.

Carnosine Dr Mercola

Dr Mercola ....... Carnosine for Muscles

 

In a recent interview, Dr. Gabriel Cousens brought up a nutritional supplement of particular interest to vegans and vegetarians, namely carnosine. Muscle building can be particularly tricky for vegans since they don't get any animal protein in their diet, but Dr. Cousens' research has lead him to believe that vegans can compensate for the lack of protein by getting sufficient amounts of carnosine.

I was intrigued with Dr. Cousens' concept when he introduced it to me, so I decided to invest a few hours and scour the medical literature for evidence in support of it. As a result, I also interviewed Dr. Craig Sale, an expert in sports physiology and nutrition, to get his opinion on it. He's a wealth of knowledge on this topic, so to get the full scoop, I highly recommend listening to the entire interview or reading through the transcript.

Interestingly enough, not only is there some evidence suggesting it can be helpful for vegans but it also plays a significant role in muscle performance and muscle soreness.

What is Carnosine, and How Can it Benefit Your Muscles?

Carnosine is a pluripotent dipeptide composed of two amino acids, beta-alanine and histadine, found in many tissues but most notably in your muscles. It serves several important roles, two of which are:

  1. 1.Buffering acids in your muscle and
  2. 2.Serving as a potent antioxidant

It appears particularly useful for improving anaerobic high intensity exercise performance, but both of the functions mentioned above also explain how carnosine may help reduce muscle soreness.

As mentioned in Steady Health, damaged muscles become inflamed, which can cause soreness. Since carnosine is a potent antioxidant, in your muscle, its presence can serve to quell muscle inflammation. It's also a primary buffer against high lactic acid levels, as explained in a review published in the International Journal of Sport Nutrition and Exercise Metabolism in 2005.

However, if you are considering using carnosine as a supplement it is important to realize that carnosine itself is probably not that useful because enzymes rapidly break it down to its constituent amino acids (beta-alanine and histidine), which are then absorbed by your muscles and re-formed  back into carnosine.

Most studies find that if you want to increase athletic performance with carnosine, your best bet is to use beta-alanine instead, since beta-alanine appears to be the rate limiting amino acid in the formation of carnosine.

Dr. Sale explains:

"One of the critical things to understand is that we talk about beta-alanine supplementation to increase muscle carnosine levels in the muscle. We do that because beta-alanine is the right limiting step to carnosine synthesis, primarily due to the fact that it's held in low concentration in your muscle. It's got a higher Km with muscle carnosine synthase, which is the enzyme responsible for the formation of carnosine in the muscle."

The reason you want to have higher, or optimal, concentrations of carnosine in your muscle is because when you perform high intensity exercise, metabolites such as hydrogen ions accumulate in your muscle, which can disrupt the "contractile machinery" in your muscle and lead to fatigue.

As your muscle accumulates hydrogen ions, you reduce the pH, making the muscle more acidic. The theory behind beta-alanine supplementation is that by improving the levels of carnosine in your muscle, you can counteract the detrimental effect of these hydrogen ion, thereby enabling you to continue muscle contraction in the high intensity exercise for a longer period of time.

Beta-Alanine for Improved Performance and Reduced Muscle Soreness

A 2002 study demonstrated that athletes have a greater requirement for carnosine stores in their muscles and may be a factor determining their performance during high-intensity exercise, such as Peak 8 or strength training.

Beta-alanine has also been shown to be helpful for preventing muscle soreness when working out.

An interesting study on carnosine published last year states that:

"Recent studies have shown that the chronic oral ingestion of ?-alanine can substantially elevate (up to 80 percent) the carnosine content of human skeletal muscle.

Interestingly, muscle carnosine loading leads to improved performance in high-intensity exercise in both untrained and trained individuals. Although carnosine is not involved in the classic adenosine triphosphate-generating metabolic pathways, this suggests an important role of the dipeptide in the homeostasis of contracting muscle cells, especially during high rates of anaerobic energy delivery.

Carnosine may attenuate acidosis by acting as a pH buffer, but improved contractile performance may also be obtained by improved excitation-contraction coupling and defence against reactive oxygen species. High carnosine concentrations are found in individuals with a high proportion of fast-twitch fibres, because these fibres are enriched with the dipeptide.

Muscle carnosine content is lower in women, declines with age and is probably lower in vegetarians, whose diets are deprived of ?-alanine."

So, should you use a supplement?

My impression is that although there are a number of useful dietary dipeptides like carnosine that might help with athletic performance, muscle building and soreness, the average person is still best served getting them from foods rather than supplements.  The foods with the highest amount of useful dietary dipeptides like carnosine would be animal proteins, like eggs, whey protein, poultry and beef.

Since vegans avoid animal proteins and are deficient in carnosine-this is why Dr. Cousen recommends it as a supplement to his vegan patients.

Remember, that if you are a vegan or just want to improve your athletic performance and   do decide to take a supplement, I recommend taking its primary precursor, beta-alanine, rather than carnosine, based on the science in this area. Dr. Sale agrees on this point. Beta-alanine is also a far less expensive supplement, compared to carnosine.

Another Beneficial Supplement for Optimal Muscle Performance

Another "supernutrient" worth mentioning here is astaxanthin—one of the most potent antioxidants known to date. For example, it's far more powerful than beta-carotene, alpha-tocopherol, lycopene and lutein, all of which are members of its chemical family.

Astaxanthin is produced by the microalgae Haematoccous pluvialis when its water supply dries up, forcing it to protect itself from ultraviolet radiation. It exhibits VERY STRONG free radical scavenging activity, and protects your cells, organs and body tissues from oxidative damage, and has been shown to help improve muscle endurance, workout performance and recovery.

It also reduces inflammation from all causes, including workout injuries, and even enhances your ability to metabolize fat!

Mice given astaxanthin were found to have accelerated body fat reduction (i.e., "fat burning") when combined with exercise, as compared to exercise alone in a 2007 study. The researchers reported that astaxanthin seems to exert this effect by protecting the function of a lipid transport enzyme on the membrane of mitochondria that "fuels" energy production.

The end result?

Buff mice. Not that the world needs more physically fit rodents, but what works on mice often works on YOU.

Another Option: Using Acceleration Training

Aside from using a beta-alanine supplement, or eating foods high in carnosine or its precursors, there's an entirely different option that can help build and strengthen muscles while at the same time reducing muscle soreness.

The alternative I'm thinking of is called Whole Body Vibrational Training (WBVT), also known as Acceleration Training using a Power Plate. By stimulating your white muscle fibers—which are your fast- and super-fast muscle fibers—the Power Plate kick-starts your pituitary gland into making more growth hormone (HGH), which helps you build lean body mass and burn fat. Another great effect of HGH is its ability to accelerate tissue healing.

Acceleration Training is quite different in that the vibrating plate targets your entire body, focusing on fully integrated motor and neurological patterns, which allows you to work ALL your muscles, and nerves, all at the same time.

It's a truly revolutionary approach to fitness because it addresses your neuromuscular system as a whole, rather than one limb or muscle group at a time. Not to mention it's time efficient, allowing you to trim off several precious hours per week from your workout time.

When used together with my Peak Fitness program, which includes Peak 8; a series of powerful high-intensity burst-type exercises, you can complete your entire workout a fraction of the time you'd have to spend on traditional workouts.

Acceleration training using the Power Plate is really the perfect complement to Peak 8 to build strength, shed excess fat, and improve athletic performance. Both of these techniques also help you produce growth hormone (HGH) naturally.

How the Power Plate Works

The Power Plate works by vibrating in three-dimensions, or three planes: vertical, horizontal and sagittal (up and down). By moving very quickly (25 to 50 times per second) across a very short distance (two to four millimeters), you aren't knocked off balance, but the complex movement is just enough that your muscles have to continuously accommodate.

  • When the Power Plate vibrates up and down, your muscle tone improves.
  • The left to right and front to back movements improves your balance and coordination.

The net result is a dramatic improvement in strength and power, flexibility, balance, tone and leanness. But that's not all.

When you stand on the vibrating Power Plate, each muscle in your body reacts in a continuous flow of micro adjustments, expanding and contracting reflexively. Just like when your leg automatically jerks after your physician taps it with his reflex hammer, your muscles react automatically to the Power Plate's vibrations—25 to 50 times per second. Stimulating your muscles and nerves this way results in more work being done by your body in a shorter period of time—with FAR greater recruitment of your muscle fibers.

Just 12-25 minutes of Acceleration Training, three days a week, is really all you need.

The Many Benefits of Acceleration Training

Aside from the benefits already mentioned, Acceleration Training has also been shown to provide:

  • Immediate improvement in blood circulation
  • Improved range of motion
  • Improved proprioception and balance
  • Increased bone density
  • Faster recovery from injury
  • Reduced pain and soreness

Which brings us right back to the issue of sore muscles...

While the jury is still out on what causes delayed onset muscle soreness (DOMS), there are strategies to help reduce muscle fatigue and soreness, whether you're a professional athlete or not.

To summarize, eating a diet that includes naturally-occurring carnosine, i.e. animal protein such as organic grass-fed beef or free-range chicken, or taking a beta-alanine supplement, and using a Power Plate can all help.

Broccoli Sprouts and Cancer

broccoli sprouts

 

Did You Know…that broccoli sprouts are a natural cancer cure, the second leading cause of death in the United States? These humble young plants that look like alfalfa and taste peppery (like radishes) pack a powerful cancer-prevention punch.

Natural cancer cure and preventions are gaining increasing attention, since according to the National Cancer Institute, at least 35% of cancer deaths are connected to diet. And while you’ve already heard that broccoli is one of the most powerful natural cancer-fighting super foods available, numerous studies have confirmed that broccoli sprouts offer even more intense benefits than the mature plant.

That’s because broccoli is a natural cancer-fighting compounds — such as sulforaphane – are most concentrated in the sprouts. For example, just one ounce of broccoli sprouts contains more sulforaphane than two pounds of broccoli.

Sprouts Contain 20 to 50 Times or More Cancer-Protective Compounds

“Three-day-old broccoli sprouts consistently contain 20 to 50 times the amount of chemo protective compounds found in mature broccoli heads, and may offer a simple, dietary means of chemically reducing cancer risk,” says Paul Talalay, M.D., J.J. Abel, Distinguished Service Professor of Pharmacology.

Talalay’s research at John Hopkins included a study with rats. One group received broccoli sprouts while the control group received nothing. Both groups were exposed to a carcinogen,dimethylbenzanthracene. The broccoli sprouts group not only developed far fewer tumors, but the tumors that did develop were smaller and grew much more slowly.

“In animals and human cells, we have demonstrated, unequivocally, that this compound (sulforaphane) can substantially reduce the incidence, rate of development, and size of tumors,” said Talalay.

Carcinogenic Detox

The John Hopkins study is just one example of a huge body of important research on similar theories. To date, more than 700 studies have examined the link between cruciferous vegetables, sulforaphane, and cancer prevention.

In another such study, 100 individuals were given broccoli sprouts and 100 others were given a placebo. The broccoli sprouts group showed a significant decrease in a biomarker for DNA damage. This decrease strongly suggests enhanced carcinogenic detoxification. Put simply, those who ate the broccoli sprouts were cleansed of cancer-causing substances.

Preventing Stomach Cancer

In yet another series of studies, Japanese researchers discovered an exciting link between broccoli sprouts and Helicobacteri pylori (H. pylori) infection. H. pylori is known to cause gastritis and believed to be a major factor in peptic ulcer and stomach cancer.

The researchers found that a diet rich in broccoli sprouts significantly reduced Helicobacteri pylori (H. pylori) infection among a group of 20 individuals.

“Even though we were unable to eradicate H. pylori, to be able suppress it and relieve the accompanying gastritis by means as simple as eating more broccoli sprouts is good news for the many people who are infected,” said Akinori Yanaka, the study’s lead investigator.

Stopping the Spread of Cancer with 13C

Broccoli and Brussels sprouts may also help stop the spread of cancer, because consuming them prompts the body to produce a substance known as 13C (indole-3-carbinol). Researchers at the Ohio State University have found exciting evidence for 13C’s ability to fight cancer cells’ proliferation.

The research was published recently in Cancer Prevention magazine, and focused on breast cancer cells. Nearly half of breast cancer patients — especially those with advanced, life-threatening cancer — have escalated levels of a molecule called Cdc25A.

“Cdc25A is present at abnormally high levels in about half of breast cancer cases, and it is associated with a poor prognosis,” said study leader Xianghong Zou, assistant professor of pathology at the Ohio State University Medical Center.

But the good news is that 13C attacks and destroys both Cdc25A and breast cancer cells. What’s more, researchers believe 13C can also fight other cancers and possibly even reverse Alzheimer’s disease .

An Easy to Grow, Easy to Eat Natural Cancer Cure

You can easily grow broccoli sprouts at home, if you wish. Many health food markets and co-ops carry broccoli seeds, and all you need to do is soak the seeds for a few days, keeping them moist and rinsing them once a day.

By day 3, the seeds will sprout. In 3 more days, the sprouts will attain their maximum carcinogen detoxifying properties.

Broccoli sprouts are easily incorporated into your cooking repertoire. Just add the sprouts to salads, sandwiches, pasta dishes, or spreads, or use them as edible garnishes.

Meanwhile, you can take heart in knowing that you’re enjoying some of the strongest possible natural cancer cure available at your local grocery store or your backyard!


Article from Underground Health Report

VitK Dr Mercola

Dr Mercola ......... Vit K

It’s been over 10 years, since I began educating and helping people understand the importance of vitamin D… specifically, vitamin D3.

Of course, I wasn’t alone in this effort. Many others contributed to helping overcome some of the myths about sunlight and how critical vitamin D3 is to your overall health.

And now I believe another nutrient, appropriately labeled the ’forgotten vitamin,’ is about to explode in popularity as researchers are uncovering more of its spectacular health benefits every day.

Why has it been forgotten and somewhat ignored for over 80 years?

I’m not sure anyone can really answer why this vitamin’s health-enhancing benefits have been so overlooked. But certainly there’s a clue to its importance here because in some areas of the world (like India), government health agencies regulate this vitamin.

If this nutrient did not have any beneficial health advantages, why would it be regulated by government health agencies?

Plus, your potential benefits from this extraordinary nutrient are pretty much off the chart.

For example, this vitamin…

  • Helps you build strong bones and keep them healthy*
  • Helps boost your vascular (arteries and veins) system*
  • Promotes your healthy heart*
  • Helps you fight against premature aging*
  • Enhances your memory function*

And this is just a start…

Before I get into more details on this vital nutrient, I must warn you up front… there are synthetic forms of this nutrient that may put your health at risk.

So, it’s very important to make sure you fully understand what to look for.

After all, the whole purpose here is to give more exposure to the ‘forgotten vitamin’ so you can reap the benefits… not to spike any health risk.

And that’s exactly what I’m planning to do. Just please pay close attention to the details on the different types of this nutrient to avoid potentially risky synthetics.

Next, let’s discover…

Why You Could be Deficient in this Vital Nutrient

It’s hard to understand why this vitamin has been so overlooked over the years. And estimates range as high as 99% of the population could be deficient in this nutrient.

There are many conditions where you could be putting yourself at risk for a higher likelihood of deficiency.

First of all, this vitamin is fat-soluble.

What does that mean? Well, fat-soluble simply means that dietary fat is necessary for efficient absorption.  So, if your diet does not contain adequate amounts of dietary fat, your absorption of this nutrient could be impacted.

There are additional conditions that could increase your risk of deficiency in this essential vitamin…    

  • Eating a poor or restricted diet
  • Having certain conditions like Crohn’s, ulcerative colitis, celiac, and others that interfere with nutrient absorption
  • Dealing with a liver condition that interferes with vitamin storage
  • Taking certain medications such as broad-spectrum antibiotics, cholesterol drugs, and potentially aspirin that may impact or block vitamin absorption
  • Eating foods containing the wrong type of this vitamin with poor bioavailability

I’m ready to dive into your best natural source of this ‘forgotten vitamin’… but first, right up front, I want to further raise your awareness of…

Synthetic Pretenders – What to Look For and Avoid

If you haven’t figured out what the ‘forgotten vitamin’ is by now let me tell you that this new wonder kid on the block is vitamin K.  You can rest assured that in the next few years you will hear the media rave about its benefits. 

But fortunately, since you are reading Mercola.com you can learn about this long before the rest of population discovers its benefits.

Danish scientist, Dr. Henrik Dam, discovered vitamin K in 1929. The ‘K’ is for ‘koagulation’ – essential for blood clotting.* But it only starts there.

Vitamin K is unique because it has multiple effects in your body, but doesn’t demonstrate any known toxicity. With research focused on potential effects on your skeletal system, brain, liver, and pancreas, vitamin K is one of the most promising nutrients of our time.*

But you should know about the different types. And in particular, know which synthetic type to be on the look out for.

There are three main forms of vitamin K…

  • K1 – phylloquinone, aka phytonadione
  • K2 – menaquinone
  • K3 – menadione synthetic variant

Vitamin K3 is a synthetic variant of the vitamin which I don’t recommended for human consumption… this is the one you and your family need to avoid at all costs.

Green leafy vegetables – including lettuce, broccoli, and spinach contain vitamin K1. And it makes up about 90 percent of the vitamin K in the Western-style diet.

The vitamin K which I recommend is vitamin K2 – natural, non-toxic, and made in your body as well.

Vitamin K2 includes several menaquinones (MK-n, with the ‘n’ determined by the number of prenyl side chains), such as MK-4 found in meats, MK-7, MK-8, and MK-9 found in fermented food products like cheese and natto.

What is Your Best Source of the ‘Forgotten Vitamin’?

One of the best natural sources of vitamin K2 comes from an ancient Japanese food called natto.

So, what is natto?

Natto…

  • Is a fermented soybean food
  • Contains nattokinase, a powerful beneficial enzyme rich in vitamin K2
  • Comes loaded with a healthy bacteria called bacillus subtilus that may also serve as a probiotic*

Fermented foods, like natto, typically have the highest concentration of vitamin K in the human diet. Levels of vitamin K found in natto (K2) have been shown to far exceed those amounts found in dark green vegetables (K1).

In fact, vitamin K2 concentration after the consumption of natto has been shown to be about 10 times higher than that of vitamin K1 after eating spinach.

Unfortunately, most people do not eat or enjoy many fermented foods.

And the absorption of vitamin K1 through eating green leafy vegetable is not very efficient… some research shows only about 10-15% gets absorbed even when consumed with dietary fat.  

The problem with natto is that most people do not enjoy eating it because they find it very distasteful. It has a slippery texture with a strong flavor and pungent aroma.

Some people do acquire a taste for natto over time.  But many never do.

Any wonder why most people may be deficient in vitamin K?... They simply may not be eating the right food to provide what’s needed.

So, what can be done to solve this issue? That’s where I can offer some recommendations to help out.

Before we dive into that, I first want to address the natto issue and the fact that it comes from soy. If you’ve been a visitor to my site, you’re probably already aware that I’m not a big fan of soy. But if you look closely, there is one exception and that’s…

Why This Type of Soy Could be Healthful for You

Like I said, I’m not an advocate of eating unfermented soy.

Why?

Many people still believe unfermented and processed soy products like soy milk, soy cheese, soy burgers, and soy ice cream are actually healthful when nothing could be further from the truth.

Today’s high-tech processing methods leave toxic and carcinogenic residues created by high temperatures, high pressure, alkali and acid baths, and petroleum solvents in unfermented soy.

Natto does not come from unfermented soy… it’s derived from healthful fermented soy and provides an extraordinary rich source of vitamin K2.

Fermented Dairy – Another Excellent Source of Vitamin K2

 

While natto is the most potent natural source of vitamin K2, the nutrient is also readily available in fermented dairy products, especially cheeses.

Most cheeses are rich in vitamin K2… particularly, curd cheese. And even though it’s not as high in vitamin K2 as natto, curd cheese may be more palatable on a day-to-day basis for many people. Raw curd cheese made from grass fed cows would be best.

Like I mentioned earlier, most people have a difficult time acquiring a taste for natto… especially on the regular basis needed for healthy K2 absorption.

Curd cheese is also a good vitamin K2 source because it’s lower in fat (animal fat) than regular cheese.

When compared to natto in equal portions… Japanese food natto contains over 27 times more vitamin K2 than curd cheese.

No Good Vitamin K2 Test

One of the reasons vitamin D became so popular is that a relatively inexpensive test became commercially available in the 1990s.  That allowed researchers and clinicians to gain a better understanding of vitamin D.  Unfortunately there really isn’t a great commercial assay for vitamin K2 yet.

Sure there is a blood test.

But, this classic measure of vitamin K deficiency uses clotting time and what’s called ‘prothrombin’… which provides almost no value for determining vitamin K deficiency in your bones or arteries.

In fact in some cases, blood levels of vitamin K may appear normal while a real deficiency exists in your bones.

So, more work needs to be done in the area of vitamin K deficiency testing.

As this ‘forgotten vitamin’ gets more and more of the attention it deserves, I’m confident modern medical science will determine a more accurate test… just like the comprehensive test eventually created for vitamin D.

With potential health advantages (in addition to the ones already mentioned above) in which vitamin K has been shown to…

  • Promote your heart health*
  • Protect and support your skin*
  • Provide the calcium path ‘key’ from your bloodstream to your bones*
  • Boost your overall immune system*
  • Help regulate calcification of your tissues*
  • Provide you powerful antioxidant benefits*
  • Protect your cells against oxidative damage*
  • Aid in supporting your already normal blood sugar levels*

… it's only a matter of time before a more comprehensive test evolves.

In the meantime, it’s important you take vitamin K deficiency seriously and take action to provide yourself and your loved ones with enough vitamin K.

And if you do not like the taste of natto, or prefer not to eat curd cheese, I have a phenomenal solution for you coming up.

But next, let’s take a closer look at…

How This Vitamin Goes to Work for YOU

While other nutrients are important for maintaining and promoting your bone health (like vitamin D3, calcium, and magnesium), evidence continues to grow indicating a vital role vitamin K plays in bone metabolism and healthy bone growth.*

In fact it may be the modern day “missing link” to increasing your bone density.

Vitamin K has been linked to osteoblasts, the cells that generate or ‘lay down’ bone and produce a specific protein known as osteocalcin.*

You can think of osteocalcin like the studs in the wall of your house. Basically, osteocalcin acts as the structural framework holding calcium in place in your bones.*

And vitamin K is critical for producing osteocalcin protein.*

Why is this so important? Because osteocalcin cannot perform its job until vitamin K converts it to an active bone-building form.

The bottom line – vitamin K is the ‘key’ that unlocks the door from your bloodstream to let calcium flow into your bones and bone marrow.*

Without this vitamin K key action, you simply wouldn't have the strong bones you do.* Plus, there’s another area vitamin K plays an important role, particularly vitamin K2.

I mentioned earlier how osteoblasts are important cells responsible for bone formation.

Well, while these osteoblast cells are busy building bone, other cells called osteoclasts are trying to break down bone and remove bone tissue.

Vitamin K2 is so important because, not only has it been shown to stimulate and enhance osteocalcin production, it has also been shown to inhibit osteoclasts and help maintain your bones.*

Some Compelling Research

There are many research studies supporting how vitamin K2 works to help maintain healthy bone mass and growth through its effects on osteocalcin, osteoblasts, and osteoclasts.*

Here are few examples for reference purposes…

  • Journal of Bone and Mineral Research, 1997, Y. Koshihara and K Hoshi
    Journal reference: “The results proved that vitamin K2 increased Gla-containing osteocalcin, which accumulated osteocalcin in the extracellular matrix, and facilitated mineralization in vitro.”
  • Molecular and Cellular Biochemistry, 2001, ZJ Ma and M Yamaguchi
    Journal reference: “These results suggested that MK-7 (K2-7) has a suppressive effect on osteoclasts.”
  • Molecular and Cellular Biochemistry, 2001, M Yamaguchi et al1
    Journal reference: “This study demonstrates that MK-7 (K2-7) has an anabolic effect on bone tissue and osteoblastic (MC3T3-E1) cells in vitro, suggesting that the compound can stimulate osteoblastic bone formation.”

In a human study, Japanese scientists examined the effect of vitamin K2 from fermented soybeans on normal individuals.

The scientists reached the following conclusion – “This illustrates that intake of K2-7 can stimulate carboxylation (gamma-carboxylated osteocalcin), which plays an important role in bone formation in normal individuals.”

So, the evidence is quite compelling when it comes to the vital role vitamin K2 potentially plays in promoting your healthy bones.*

What is the Best Way for You to Get Vitamin K2?

Since I promised you an alternative natto solution for vitamin K2, let’s get right to it.

The bottom line here… your best bet for a natural source of K2 is from natto. And maybe you can find a reliable natural source and come to acquire a taste for it.

But I can tell you… I tried it myself on a regular basis but never really got used to the taste and smell. So, I decided to do the next best thing and look for a high quality inexpensive natural K2 supplement made from natto.

And let me tell you, finding a natural source of vitamin K2 turned out to be a real challenge.

Why? Well, not only did my team and I have to be on the lookout for risky synthetic imposters out there, we had to scrutinize the manufacturing processes very closely as well.  

See, as I dug deeper and deeper into this, it became quite apparent how important a role the manufacturer must play in creating a natural high-quality K2 product.

Here are the key issues my team and I looked for when searching for a top manufacturer to deliver the highest quality vitamin K2 formula…

  • Must be non-GMO – Formulas including genetically modified organisms or processes are absolutely unacceptable.
  • Must be allergen-free – Other than fermented soy content from the soybeans, the formula has to be free from known allergens such as peanuts, tree nuts, milk, eggs, fin fish, shellfish, and wheat.
  • Must have a stable fermentation process – Natto fermentation process that involves other derivatives can be very unstable. Need a consistent reliable process that ensures product quality in the formula.
  • Must use vitamin K2-7 in the formula – Just like there are many varieties of vitamin K (K1, K2, K3), there are many varieties of K2. K2-7 produced from natto has proven to be one of the most bioavailable, stable, and beneficial varieties.*
  • Must be pure – Formula must be of the purest fashion with both internal and external lab validations following GMP standards and high-quality best practices.
  • Must be affordable – With all these rigorous requirements for this K2 formula, cost could be a real challenge. But affordability is one of my top priorities and cannot be overlooked.

The good news with all this is I was able to find, what I believe to be,  the highest quality vitamin K2 manufacturer in the world that could deliver the formula you need. 

Plus, this manufacturer not only met all of the stringent selection criteria, they exceeded many of them as well.

I’ll have more on that coming right up. But first I want to take a closer look at another reason why the vitamin K2 type requirement is so important.

Powerful Synergy with Vitamin D3

 

The surprising thing about what I’m going to review next is that some of the research has been available for over 10 years.

I guess this goes along with the whole ‘forgotten vitamin’ story.

If you’ve been a regular visitor to this site, you undoubtedly know how I feel about the vital role vitamin D3 plays in your optimal health.

Well, the amazing thing is research has shown vitamin K2 and vitamin D3 may provide you another level of benefits when taken together.*

Several studies have shown the following potential synergistic benefits when vitamin K2 and D3 are combined…

  • Increased bone formation*
  • Enhanced osteocalcin accumulation in cells*
  • Amplified bone mineral density*

So, vitamin K2 and D3 worked together in certain situations to help improve your bone health even more.*

Because vitamin D3 encourages calcium uptake to promote your strong and healthy bones, it’s not only a natural complement to vitamin K2, the two nutrients work together to boost your bone health to a higher level.*

What a phenomenal combination. Wouldn’t you agree?

Manufacturer’s Report Card for Producing this Health-Boosting Formula*

I mentioned earlier how I found a unique manufacturer of vitamin K2 that not only met my demanding requirements, but exceeded them.

Here’s a handy chart showing you how this selected K2 producer stacks up… and then next we’ll get into more details on how they exceeded my expectations.

Selection criteria:

Mercola manufacturer?

Other manufacturers?

Must be non-GMO

  • Yes – The product is not genetically modified in either the processes or the ingredients.

Some synthetic manufacturers of vitamin K3 and K2 natural formula ‘pretenders’ use GMOs.

Must be allergen-free (other than soybeans)

  • Yes – This manufacturer not only avoids using known allergens, it has effective procedures in place to avoid cross contamination during production processes.

Not all manufacturers of vitamin K2 go through both painstaking processes to avoid cross contamination and avoid allergen ingredients in their formulas.

Must be non-animal sourced

  • Yes – No animal sources are used in the formulation process

Some manufacturers may use animal sourced ingredients to create their vitamin K formula.

Must have a stable fermentation process

  • Yes – Stability and consistent high-quality are this manufacturer’s forte. Shelf life of K2 product is over 2 years. And not only do they have a dedicated facility for producing K2, they also filed a drug master file (DMF) fully characterizing the product to help ensure stability.

Very few if any manufacturers have dedicated facilities for producing vitamin K2 and even fewer ever file a DMF to characterize their formula.

Must use vitamin K2-7 in the formula

  • Yes – Only vitamin K2-7 (from natto fermentation) gets produced by this manufacturer in its dedicated facility in India.

There are many synthetic formulas of vitamin K (K3) produced that could be risky to your health. Plus, other varieties of vitamin K2 produced may not be as beneficial.

Must be pure

  • Yes – This manufacturer ensures purity by using a dedicated facility, adhering to GMP standards, and by voluntarily fully characterizing its K2-7 formula by filing DMFs.

To date, my team could not find any other manufacturer who followed such rigorous purity standards as this. To our knowledge, no other manufacturer has submitted a DMF for their vitamin K2.

Must be affordable

  • Yes – This is a big sticking point with the complex processes involved to produce K2-7. Yet, by using natto and a dedicated facility, economies of scale have kept costs reasonable.

Many forms of vitamin K2, and particularly K2-7, can be very expensive and almost prohibitive from practical use.

So, you can see how this manufacturer met my selection criteria with flying colors.

But what about the ways they exceeded (that I mentioned earlier)?

Well, I feel the biggest area they exceeded my expectations was with the…

Drug Master File – How Our Manufacturer Clearly Stands Above the Crowd

The comparison chart above introduced you to a new concept called drug master file (DMF).

The manufacturer I chose to provide vitamin K2 voluntarily submitted these types of files in India. Since it conforms to strict standards, the DMF can be used in any country.

What is a DMF and why is it so important here?

A Drug Master File (DMF) is a submission that may be used to provide confidential detailed information about facilities, processes, or articles used in the manufacturing, processing, packaging, and storing of one or more human drugs..

The astonishing thing about a DMF…it’s totally voluntary.

So, why would any manufacturer wish to expose their formula, facilities, processes, etc., when they don’t have to?

Well, that’s exactly why I chose this manufacturer to provide the vitamin K2 formula I was looking for… they have nothing to hide and go to the ‘nth degree’ to ensure stability and consistency of their formula.

In fact, to our knowledge, this manufacturer is the only one who has filed DMFs for vitamin K2.

Their Type II and Type III DMF submissions totally expose...

  • Formula substance and…
  • Materials used in the formula preparation and…
  • Packaging materials

Plus, the fact they have a dedicated and certified cGMP facility to only produce K2-7, speaks volumes for their commitment to purity and cross contamination protection.

Now you know why I only recommend Vitamin K2 as your source of vitamin K.

And there’s another area where this manufacturer’s dedicated facility in India comes into play…

How Production Costs are Kept in Check to Make the Formula Affordable

Many sources of vitamin K2 supplements tend to be expensive.

So, why is Vitamin K2 able to be reasonably priced?

It really all boils down to many of the same things we’ve already talked about that this manufacturer does. Things like…

  • Economies of scale – By using a dedicated facility for vitamin K2-7, costs are more easily kept in check. Potential costly cross contamination issues from other formula lines are avoided. Manufacturer spent over 4 years building this super-efficient facility dedicated to vitamin K2 production.
  • Efficient fermentation processes – By using natto from fermented soybeans to produce the Vitamin K2 formula, this is one of the most cost-efficient processes to yield vitamin K2-7.
  • Leveraging competitive advantages – Many competitors are composed of very large companies (one is a Japanese billion-dollar conglomerate) that have very expensive overhead and processes to produce K2. Not so, with the Vitamin K2 manufacturer.

11 Powerful Reasons Why I Strongly Recommend this Formula

Let me quickly summarize the extraordinary potential benefits to your overall health from vitamin K2 – available in the Vitamin K2 formula…

 

  • Helps you build strong bones and keep them healthy*
  • Helps boost your vascular (arteries and veins) system*
  • Protects your cells against oxidative damage*
  • Promotes your heart health*
  • Protects and supports your skin*
  • Helps you fight against premature aging*
  • Provides calcium path ‘key’ from your bloodstream into your bones*
  • Boosts your memory function*
  • Helps regulate calcification of your tissues*
  • Provides you powerful antioxidant benefits*
  • Aids in supporting your already normal blood sugar levels*

These powerful benefits tell an incredible story about vitamin K2… rather amazing it’s been ‘forgotten’ for so long.

But keep in mind, without the high-quality manufacturer focused on stable and pure production of this nutrient built into the Vitamin K2 formula, your benefits could be significantly reduced.

Don’t just settle for any vitamin K or K2 supplement. Do like I do… demand the absolute best you can find.

And that’s exactly what I believe you have with Vitamin K2.

Isn’t It Time to Protect You and Your Loved Ones from
Potential Vitamin K2 Deficiency?

By now, you should be aware how the ‘forgotten vitamin’ needs to be recognized and actions taken to reduce your potential deficiency.

And just to remind you why I’ve chosen this Vitamin K2 formula over others (in addition to the phenomenal health benefits), here it is in a nutshell why I strongly recommend this formula…

  • Provides a natural and more convenient vitamin K2 alternative to consuming distasteful raw natto
  • Manufacturer meets and exceeds all of my selection criteria in delivering an extraordinary high-quality supplement at a reasonable price
  • Is the right vitamin K type (K2) that works synergistically with vitamin D3 to help boost your bone health to an even higher optimal level*

These reasons really sum up why Vitamin K2 is key in my book to helping you protect yourself from vitamin K deficiency issues.

And the fact that research has shown how vitamin K2 and D3 work so effectively together… this is certainly a fantastic added bonus for you.

This added bonus is so important I’ve decided to offer you both the individual Vitamin K2 formula and a budget-saving package with vitamin D3 as well (details below).

At only $69.97 for a 3-month supply of Vitamin K2, I believe this is a price that will rename the ‘forgotten vitamin’ for good.

So, protect yourself and your loved ones from potential vitamin K deficiencies and boost your optimal bone health today!*  Order without delay.

Also, remember you have virtually have no risk ordering this product… my 100% no-questions-asked lifetime guarantee (see details below) covers you on this.

Dr Mercola ......... Vit K

It’s been over 10 years, since I began educating and helping people understand the importance of vitamin D… specifically, vitamin D3.

Of course, I wasn’t alone in this effort. Many others contributed to helping overcome some of the myths about sunlight and how critical vitamin D3 is to your overall health.

And now I believe another nutrient, appropriately labeled the ’forgotten vitamin,’ is about to explode in popularity as researchers are uncovering more of its spectacular health benefits every day.

Why has it been forgotten and somewhat ignored for over 80 years?

I’m not sure anyone can really answer why this vitamin’s health-enhancing benefits have been so overlooked. But certainly there’s a clue to its importance here because in some areas of the world (like India), government health agencies regulate this vitamin.

If this nutrient did not have any beneficial health advantages, why would it be regulated by government health agencies?

Plus, your potential benefits from this extraordinary nutrient are pretty much off the chart.

For example, this vitamin…

  • Helps you build strong bones and keep them healthy*
  • Helps boost your vascular (arteries and veins) system*
  • Promotes your healthy heart*
  • Helps you fight against premature aging*
  • Enhances your memory function*

And this is just a start…

Before I get into more details on this vital nutrient, I must warn you up front… there are synthetic forms of this nutrient that may put your health at risk.

So, it’s very important to make sure you fully understand what to look for.

After all, the whole purpose here is to give more exposure to the ‘forgotten vitamin’ so you can reap the benefits… not to spike any health risk.

And that’s exactly what I’m planning to do. Just please pay close attention to the details on the different types of this nutrient to avoid potentially risky synthetics.

Next, let’s discover…

Why You Could be Deficient in this Vital Nutrient

It’s hard to understand why this vitamin has been so overlooked over the years. And estimates range as high as 99% of the population could be deficient in this nutrient.

There are many conditions where you could be putting yourself at risk for a higher likelihood of deficiency.

First of all, this vitamin is fat-soluble.

What does that mean? Well, fat-soluble simply means that dietary fat is necessary for efficient absorption.  So, if your diet does not contain adequate amounts of dietary fat, your absorption of this nutrient could be impacted.

There are additional conditions that could increase your risk of deficiency in this essential vitamin…    

  • Eating a poor or restricted diet
  • Having certain conditions like Crohn’s, ulcerative colitis, celiac, and others that interfere with nutrient absorption
  • Dealing with a liver condition that interferes with vitamin storage
  • Taking certain medications such as broad-spectrum antibiotics, cholesterol drugs, and potentially aspirin that may impact or block vitamin absorption
  • Eating foods containing the wrong type of this vitamin with poor bioavailability

I’m ready to dive into your best natural source of this ‘forgotten vitamin’… but first, right up front, I want to further raise your awareness of…

Synthetic Pretenders – What to Look For and Avoid

If you haven’t figured out what the ‘forgotten vitamin’ is by now let me tell you that this new wonder kid on the block is vitamin K.  You can rest assured that in the next few years you will hear the media rave about its benefits. 

But fortunately, since you are reading Mercola.com you can learn about this long before the rest of population discovers its benefits.

Danish scientist, Dr. Henrik Dam, discovered vitamin K in 1929. The ‘K’ is for ‘koagulation’ – essential for blood clotting.* But it only starts there.

Vitamin K is unique because it has multiple effects in your body, but doesn’t demonstrate any known toxicity. With research focused on potential effects on your skeletal system, brain, liver, and pancreas, vitamin K is one of the most promising nutrients of our time.*

But you should know about the different types. And in particular, know which synthetic type to be on the look out for.

There are three main forms of vitamin K…

  • K1 – phylloquinone, aka phytonadione
  • K2 – menaquinone
  • K3 – menadione synthetic variant

Vitamin K3 is a synthetic variant of the vitamin which I don’t recommended for human consumption… this is the one you and your family need to avoid at all costs.

Green leafy vegetables – including lettuce, broccoli, and spinach contain vitamin K1. And it makes up about 90 percent of the vitamin K in the Western-style diet.

The vitamin K which I recommend is vitamin K2 – natural, non-toxic, and made in your body as well.

Vitamin K2 includes several menaquinones (MK-n, with the ‘n’ determined by the number of prenyl side chains), such as MK-4 found in meats, MK-7, MK-8, and MK-9 found in fermented food products like cheese and natto.

What is Your Best Source of the ‘Forgotten Vitamin’?

One of the best natural sources of vitamin K2 comes from an ancient Japanese food called natto.

So, what is natto?

Natto…

  • Is a fermented soybean food
  • Contains nattokinase, a powerful beneficial enzyme rich in vitamin K2
  • Comes loaded with a healthy bacteria called bacillus subtilus that may also serve as a probiotic*

Fermented foods, like natto, typically have the highest concentration of vitamin K in the human diet. Levels of vitamin K found in natto (K2) have been shown to far exceed those amounts found in dark green vegetables (K1).

In fact, vitamin K2 concentration after the consumption of natto has been shown to be about 10 times higher than that of vitamin K1 after eating spinach.

Unfortunately, most people do not eat or enjoy many fermented foods.

And the absorption of vitamin K1 through eating green leafy vegetable is not very efficient… some research shows only about 10-15% gets absorbed even when consumed with dietary fat.  

The problem with natto is that most people do not enjoy eating it because they find it very distasteful. It has a slippery texture with a strong flavor and pungent aroma.

Some people do acquire a taste for natto over time.  But many never do.

Any wonder why most people may be deficient in vitamin K?... They simply may not be eating the right food to provide what’s needed.

So, what can be done to solve this issue? That’s where I can offer some recommendations to help out.

Before we dive into that, I first want to address the natto issue and the fact that it comes from soy. If you’ve been a visitor to my site, you’re probably already aware that I’m not a big fan of soy. But if you look closely, there is one exception and that’s…

Why This Type of Soy Could be Healthful for You

Like I said, I’m not an advocate of eating unfermented soy.

Why?

Many people still believe unfermented and processed soy products like soy milk, soy cheese, soy burgers, and soy ice cream are actually healthful when nothing could be further from the truth.

Today’s high-tech processing methods leave toxic and carcinogenic residues created by high temperatures, high pressure, alkali and acid baths, and petroleum solvents in unfermented soy.

Natto does not come from unfermented soy… it’s derived from healthful fermented soy and provides an extraordinary rich source of vitamin K2.

Fermented Dairy – Another Excellent Source of Vitamin K2

 

While natto is the most potent natural source of vitamin K2, the nutrient is also readily available in fermented dairy products, especially cheeses.

Most cheeses are rich in vitamin K2… particularly, curd cheese. And even though it’s not as high in vitamin K2 as natto, curd cheese may be more palatable on a day-to-day basis for many people. Raw curd cheese made from grass fed cows would be best.

Like I mentioned earlier, most people have a difficult time acquiring a taste for natto… especially on the regular basis needed for healthy K2 absorption.

Curd cheese is also a good vitamin K2 source because it’s lower in fat (animal fat) than regular cheese.

When compared to natto in equal portions… Japanese food natto contains over 27 times more vitamin K2 than curd cheese.

No Good Vitamin K2 Test

One of the reasons vitamin D became so popular is that a relatively inexpensive test became commercially available in the 1990s.  That allowed researchers and clinicians to gain a better understanding of vitamin D.  Unfortunately there really isn’t a great commercial assay for vitamin K2 yet.

Sure there is a blood test.

But, this classic measure of vitamin K deficiency uses clotting time and what’s called ‘prothrombin’… which provides almost no value for determining vitamin K deficiency in your bones or arteries.

In fact in some cases, blood levels of vitamin K may appear normal while a real deficiency exists in your bones.

So, more work needs to be done in the area of vitamin K deficiency testing.

As this ‘forgotten vitamin’ gets more and more of the attention it deserves, I’m confident modern medical science will determine a more accurate test… just like the comprehensive test eventually created for vitamin D.

With potential health advantages (in addition to the ones already mentioned above) in which vitamin K has been shown to…

  • Promote your heart health*
  • Protect and support your skin*
  • Provide the calcium path ‘key’ from your bloodstream to your bones*
  • Boost your overall immune system*
  • Help regulate calcification of your tissues*
  • Provide you powerful antioxidant benefits*
  • Protect your cells against oxidative damage*
  • Aid in supporting your already normal blood sugar levels*

… it's only a matter of time before a more comprehensive test evolves.

In the meantime, it’s important you take vitamin K deficiency seriously and take action to provide yourself and your loved ones with enough vitamin K.

And if you do not like the taste of natto, or prefer not to eat curd cheese, I have a phenomenal solution for you coming up.

But next, let’s take a closer look at…

How This Vitamin Goes to Work for YOU

While other nutrients are important for maintaining and promoting your bone health (like vitamin D3, calcium, and magnesium), evidence continues to grow indicating a vital role vitamin K plays in bone metabolism and healthy bone growth.*

In fact it may be the modern day “missing link” to increasing your bone density.

Vitamin K has been linked to osteoblasts, the cells that generate or ‘lay down’ bone and produce a specific protein known as osteocalcin.*

You can think of osteocalcin like the studs in the wall of your house. Basically, osteocalcin acts as the structural framework holding calcium in place in your bones.*

And vitamin K is critical for producing osteocalcin protein.*

Why is this so important? Because osteocalcin cannot perform its job until vitamin K converts it to an active bone-building form.

The bottom line – vitamin K is the ‘key’ that unlocks the door from your bloodstream to let calcium flow into your bones and bone marrow.*

Without this vitamin K key action, you simply wouldn't have the strong bones you do.* Plus, there’s another area vitamin K plays an important role, particularly vitamin K2.

I mentioned earlier how osteoblasts are important cells responsible for bone formation.

Well, while these osteoblast cells are busy building bone, other cells called osteoclasts are trying to break down bone and remove bone tissue.

Vitamin K2 is so important because, not only has it been shown to stimulate and enhance osteocalcin production, it has also been shown to inhibit osteoclasts and help maintain your bones.*

Some Compelling Research

There are many research studies supporting how vitamin K2 works to help maintain healthy bone mass and growth through its effects on osteocalcin, osteoblasts, and osteoclasts.*

Here are few examples for reference purposes…

  • Journal of Bone and Mineral Research, 1997, Y. Koshihara and K Hoshi
    Journal reference: “The results proved that vitamin K2 increased Gla-containing osteocalcin, which accumulated osteocalcin in the extracellular matrix, and facilitated mineralization in vitro.”
  • Molecular and Cellular Biochemistry, 2001, ZJ Ma and M Yamaguchi
    Journal reference: “These results suggested that MK-7 (K2-7) has a suppressive effect on osteoclasts.”
  • Molecular and Cellular Biochemistry, 2001, M Yamaguchi et al1
    Journal reference: “This study demonstrates that MK-7 (K2-7) has an anabolic effect on bone tissue and osteoblastic (MC3T3-E1) cells in vitro, suggesting that the compound can stimulate osteoblastic bone formation.”

In a human study, Japanese scientists examined the effect of vitamin K2 from fermented soybeans on normal individuals.

The scientists reached the following conclusion – “This illustrates that intake of K2-7 can stimulate carboxylation (gamma-carboxylated osteocalcin), which plays an important role in bone formation in normal individuals.”

So, the evidence is quite compelling when it comes to the vital role vitamin K2 potentially plays in promoting your healthy bones.*

What is the Best Way for You to Get Vitamin K2?

Since I promised you an alternative natto solution for vitamin K2, let’s get right to it.

The bottom line here… your best bet for a natural source of K2 is from natto. And maybe you can find a reliable natural source and come to acquire a taste for it.

But I can tell you… I tried it myself on a regular basis but never really got used to the taste and smell. So, I decided to do the next best thing and look for a high quality inexpensive natural K2 supplement made from natto.

And let me tell you, finding a natural source of vitamin K2 turned out to be a real challenge.

Why? Well, not only did my team and I have to be on the lookout for risky synthetic imposters out there, we had to scrutinize the manufacturing processes very closely as well.  

See, as I dug deeper and deeper into this, it became quite apparent how important a role the manufacturer must play in creating a natural high-quality K2 product.

Here are the key issues my team and I looked for when searching for a top manufacturer to deliver the highest quality vitamin K2 formula…

  • Must be non-GMO – Formulas including genetically modified organisms or processes are absolutely unacceptable.
  • Must be allergen-free – Other than fermented soy content from the soybeans, the formula has to be free from known allergens such as peanuts, tree nuts, milk, eggs, fin fish, shellfish, and wheat.
  • Must have a stable fermentation process – Natto fermentation process that involves other derivatives can be very unstable. Need a consistent reliable process that ensures product quality in the formula.
  • Must use vitamin K2-7 in the formula – Just like there are many varieties of vitamin K (K1, K2, K3), there are many varieties of K2. K2-7 produced from natto has proven to be one of the most bioavailable, stable, and beneficial varieties.*
  • Must be pure – Formula must be of the purest fashion with both internal and external lab validations following GMP standards and high-quality best practices.
  • Must be affordable – With all these rigorous requirements for this K2 formula, cost could be a real challenge. But affordability is one of my top priorities and cannot be overlooked.

The good news with all this is I was able to find, what I believe to be,  the highest quality vitamin K2 manufacturer in the world that could deliver the formula you need. 

Plus, this manufacturer not only met all of the stringent selection criteria, they exceeded many of them as well.

I’ll have more on that coming right up. But first I want to take a closer look at another reason why the vitamin K2 type requirement is so important.

Powerful Synergy with Vitamin D3

 

The surprising thing about what I’m going to review next is that some of the research has been available for over 10 years.

I guess this goes along with the whole ‘forgotten vitamin’ story.

If you’ve been a regular visitor to this site, you undoubtedly know how I feel about the vital role vitamin D3 plays in your optimal health.

Well, the amazing thing is research has shown vitamin K2 and vitamin D3 may provide you another level of benefits when taken together.*

Several studies have shown the following potential synergistic benefits when vitamin K2 and D3 are combined…

  • Increased bone formation*
  • Enhanced osteocalcin accumulation in cells*
  • Amplified bone mineral density*

So, vitamin K2 and D3 worked together in certain situations to help improve your bone health even more.*

Because vitamin D3 encourages calcium uptake to promote your strong and healthy bones, it’s not only a natural complement to vitamin K2, the two nutrients work together to boost your bone health to a higher level.*

What a phenomenal combination. Wouldn’t you agree?

Manufacturer’s Report Card for Producing this Health-Boosting Formula*

I mentioned earlier how I found a unique manufacturer of vitamin K2 that not only met my demanding requirements, but exceeded them.

Here’s a handy chart showing you how this selected K2 producer stacks up… and then next we’ll get into more details on how they exceeded my expectations.

Selection criteria:

Mercola manufacturer?

Other manufacturers?

Must be non-GMO

  • Yes – The product is not genetically modified in either the processes or the ingredients.

Some synthetic manufacturers of vitamin K3 and K2 natural formula ‘pretenders’ use GMOs.

Must be allergen-free (other than soybeans)

  • Yes – This manufacturer not only avoids using known allergens, it has effective procedures in place to avoid cross contamination during production processes.

Not all manufacturers of vitamin K2 go through both painstaking processes to avoid cross contamination and avoid allergen ingredients in their formulas.

Must be non-animal sourced

  • Yes – No animal sources are used in the formulation process

Some manufacturers may use animal sourced ingredients to create their vitamin K formula.

Must have a stable fermentation process

  • Yes – Stability and consistent high-quality are this manufacturer’s forte. Shelf life of K2 product is over 2 years. And not only do they have a dedicated facility for producing K2, they also filed a drug master file (DMF) fully characterizing the product to help ensure stability.

Very few if any manufacturers have dedicated facilities for producing vitamin K2 and even fewer ever file a DMF to characterize their formula.

Must use vitamin K2-7 in the formula

  • Yes – Only vitamin K2-7 (from natto fermentation) gets produced by this manufacturer in its dedicated facility in India.

There are many synthetic formulas of vitamin K (K3) produced that could be risky to your health. Plus, other varieties of vitamin K2 produced may not be as beneficial.

Must be pure

  • Yes – This manufacturer ensures purity by using a dedicated facility, adhering to GMP standards, and by voluntarily fully characterizing its K2-7 formula by filing DMFs.

To date, my team could not find any other manufacturer who followed such rigorous purity standards as this. To our knowledge, no other manufacturer has submitted a DMF for their vitamin K2.

Must be affordable

  • Yes – This is a big sticking point with the complex processes involved to produce K2-7. Yet, by using natto and a dedicated facility, economies of scale have kept costs reasonable.

Many forms of vitamin K2, and particularly K2-7, can be very expensive and almost prohibitive from practical use.

So, you can see how this manufacturer met my selection criteria with flying colors.

But what about the ways they exceeded (that I mentioned earlier)?

Well, I feel the biggest area they exceeded my expectations was with the…

Drug Master File – How Our Manufacturer Clearly Stands Above the Crowd

The comparison chart above introduced you to a new concept called drug master file (DMF).

The manufacturer I chose to provide vitamin K2 voluntarily submitted these types of files in India. Since it conforms to strict standards, the DMF can be used in any country.

What is a DMF and why is it so important here?

A Drug Master File (DMF) is a submission that may be used to provide confidential detailed information about facilities, processes, or articles used in the manufacturing, processing, packaging, and storing of one or more human drugs..

The astonishing thing about a DMF…it’s totally voluntary.

So, why would any manufacturer wish to expose their formula, facilities, processes, etc., when they don’t have to?

Well, that’s exactly why I chose this manufacturer to provide the vitamin K2 formula I was looking for… they have nothing to hide and go to the ‘nth degree’ to ensure stability and consistency of their formula.

In fact, to our knowledge, this manufacturer is the only one who has filed DMFs for vitamin K2.

Their Type II and Type III DMF submissions totally expose...

  • Formula substance and…
  • Materials used in the formula preparation and…
  • Packaging materials

Plus, the fact they have a dedicated and certified cGMP facility to only produce K2-7, speaks volumes for their commitment to purity and cross contamination protection.

Now you know why I only recommend Vitamin K2 as your source of vitamin K.

And there’s another area where this manufacturer’s dedicated facility in India comes into play…

How Production Costs are Kept in Check to Make the Formula Affordable

Many sources of vitamin K2 supplements tend to be expensive.

So, why is Vitamin K2 able to be reasonably priced?

It really all boils down to many of the same things we’ve already talked about that this manufacturer does. Things like…

  • Economies of scale – By using a dedicated facility for vitamin K2-7, costs are more easily kept in check. Potential costly cross contamination issues from other formula lines are avoided. Manufacturer spent over 4 years building this super-efficient facility dedicated to vitamin K2 production.
  • Efficient fermentation processes – By using natto from fermented soybeans to produce the Vitamin K2 formula, this is one of the most cost-efficient processes to yield vitamin K2-7.
  • Leveraging competitive advantages – Many competitors are composed of very large companies (one is a Japanese billion-dollar conglomerate) that have very expensive overhead and processes to produce K2. Not so, with the Vitamin K2 manufacturer.

11 Powerful Reasons Why I Strongly Recommend this Formula

Let me quickly summarize the extraordinary potential benefits to your overall health from vitamin K2 – available in the Vitamin K2 formula…

 

  • Helps you build strong bones and keep them healthy*
  • Helps boost your vascular (arteries and veins) system*
  • Protects your cells against oxidative damage*
  • Promotes your heart health*
  • Protects and supports your skin*
  • Helps you fight against premature aging*
  • Provides calcium path ‘key’ from your bloodstream into your bones*
  • Boosts your memory function*
  • Helps regulate calcification of your tissues*
  • Provides you powerful antioxidant benefits*
  • Aids in supporting your already normal blood sugar levels*

These powerful benefits tell an incredible story about vitamin K2… rather amazing it’s been ‘forgotten’ for so long.

But keep in mind, without the high-quality manufacturer focused on stable and pure production of this nutrient built into the Vitamin K2 formula, your benefits could be significantly reduced.

Don’t just settle for any vitamin K or K2 supplement. Do like I do… demand the absolute best you can find.

And that’s exactly what I believe you have with Vitamin K2.

Isn’t It Time to Protect You and Your Loved Ones from
Potential Vitamin K2 Deficiency?

By now, you should be aware how the ‘forgotten vitamin’ needs to be recognized and actions taken to reduce your potential deficiency.

And just to remind you why I’ve chosen this Vitamin K2 formula over others (in addition to the phenomenal health benefits), here it is in a nutshell why I strongly recommend this formula…

  • Provides a natural and more convenient vitamin K2 alternative to consuming distasteful raw natto
  • Manufacturer meets and exceeds all of my selection criteria in delivering an extraordinary high-quality supplement at a reasonable price
  • Is the right vitamin K type (K2) that works synergistically with vitamin D3 to help boost your bone health to an even higher optimal level*

These reasons really sum up why Vitamin K2 is key in my book to helping you protect yourself from vitamin K deficiency issues.

And the fact that research has shown how vitamin K2 and D3 work so effectively together… this is certainly a fantastic added bonus for you.

This added bonus is so important I’ve decided to offer you both the individual Vitamin K2 formula and a budget-saving package with vitamin D3 as well (details below).

At only $69.97 for a 3-month supply of Vitamin K2, I believe this is a price that will rename the ‘forgotten vitamin’ for good.

So, protect yourself and your loved ones from potential vitamin K deficiencies and boost your optimal bone health today!*  Order without delay.

Also, remember you have virtually have no risk ordering this product… my 100% no-questions-asked lifetime guarantee (see details below) covers you on this.